Search results for "Pi phenotypes"

showing 2 items of 2 documents

On the genetics of the pi serum proteins.

1970

The authors report family studies (51 families with 134 children) on the inheritance of the Pi phenotypes. Combining these data with a Norwegian family material (77 families with 323 children) published by Fagerhol and Gedde-Dahl (1969) a total of 128 families with 457 children is now available, which allows the following conclusion: The Pi phenotypes are inherited by a simple codominant mode of heredity and they are determined by a set of (at least nine) alleles. As up to now no exception to the role of inheritance has been observed, the application of the Pi system in cases of disputed paternity seems to be discussible. Some methodological problems in connection with this are shown.

GeneticsMaleInheritance (genetic algorithm)NorwegianPi phenotypesBiologymedicine.disease_causelanguage.human_languageHuman geneticsFamily studiesGenetics PopulationPhenotypeHeredityGeneticslanguagemedicinePiHumansFemaleAlleleTrypsin InhibitorsGenetics (clinical)AllelesHumangenetik
researchProduct

Hp, Gc, Cp, Tf, Bg and Pi phenotypes in leprosy patients and healthy controls from West Bengal (India)

1972

On a sample of n=601 leprous individuals and n=386 healthy controls from West Bengal (India) the question is discussed, if there are existing any associations between leprosy and several serum protein groups like haptoglobin, Gc, ceruloplasmin, transferrin, β2 I and Pi. No associations were found concerning the haptoglobins and transferrins. Certain associations came out respecting ceruloplasmin, β2 I and Pi phenotypes. However, these associations, which were found in connection with the different types and clinical courses of leprosy, should be reexamined by further research. The most striking results were obtained concerning the Gc proteins. In accordance with previously performed investi…

Serum proteinIndiaGene FrequencyLeprosyGeneticsmedicineHumansMetabolic diseaseGenetics (clinical)Glycoproteinschemistry.chemical_classificationPolymorphism GeneticHaptoglobinsbiologyHaptoglobinTransferrinCeruloplasminPi phenotypesmedicine.diseasePhenotypechemistryTransferrinImmunologybiology.proteinSerum GlobulinsWest bengalLeprosyFactor Analysis StatisticalCeruloplasminHuman Genetics
researchProduct